Yes. Factory calibration is a good starting point, but it does not replace profiling your specific monitor in your actual workspace.

Calibration and profiling are related but different:

• Calibration adjusts the display itself, such as grayscale neutrality, white point, and tone response.
• Profiling measures how the calibrated monitor actually renders color and creates an ICC profile so the OS and color-managed apps can display color more accurately.

Why profile anyway?

• Monitors drift over time as components age.
• Your room lighting and viewing conditions affect the best target settings.
• A custom profile can make finer corrections than a generic factory setup.
• It helps color management map image colors to your display more accurately.

If you skip profiling, the monitor will still work, but you may not get the color accuracy and consistency you paid for. Factory calibration may have been accurate when shipped, but it may no longer be optimal once the monitor is in your environment or after some use.

So: even with a factory-calibrated Adobe RGB monitor, profiling is still beneficial, and recalibrating/profiling periodically is the best practice.