Yes, but it may be hidden. A unit-focus macro (the old school, where the lens elements are in a more-or-less fixed relationship to one another and the whole shebang is moved further away from the sensor/film plane) will usually work in exactly the same way as extension tubes. The lens is essentially a well-corrected ordinary lens with a built-in adjustable helicoid extension tube, and you need to be aware of the lens draw when metering externally. (When metering in-camera, the electronics take care of the hassle for you.)

Newer internal-focus (or rear focus) macros (and non-macros for that matter) actually focus by changing the focal length of the lens. The front element stays anchored in space, and the focal length of the lens is reduced. That does two very noticable things. First, there is no "focus breathing" -- the subject will stay the same size in the frame as you focus. Secondly, and most pertinently for your question, the size of the physical aperture stays the same as the focal length is decreased, so the effects of lens draw are masked (or moderated, depending on the individual lens) by an ever-increasing relative aperture as you focus closer. So with a "pure internal focus" design, at infinity you may have a lens that is 100mm set at, say, f/8, but when you focus much closer, you may actually have a 75mm lens at f/6 (using the same 12.5mm apparent aperture), but the lens draw due to focus reduces the light to the same level as it would have been at f/8. The physical length of the assembly is unchanged, so the relative aperture of the whole remains the same if the physical aperture is unchanged.

And just to complicate matters a bit further, some lenses seem to be of a hybrid design -- they use both internal focus and ordinary extension to get where they're going. That's not a problem with TTL metering, but it would mean creating a draw chart for use with an external meter. A couple of test shots with a grey card and manual exposure settings will tell you whether or not you need to go to the trouble of creating one.