Yes, but it will likely require trial and error. Uncoated watercolor paper behaves very differently from inkjet-coated papers, so ready-made ICC profiles are unlikely to be available or useful.

The main issue is ink handling: uncoated paper will absorb and spread ink differently, so you’ll need to experiment with lower-ink-type settings rather than settings intended for heavy coated fine-art papers. A plain paper/ordinary office paper type setting is a reasonable starting point because it generally lays down less ink.

For printer safety, if you’re unsure about head clearance, use the largest platen gap setting. That reduces the chance of the print head striking the thicker, rougher paper.

So in short:

• expect testing rather than a perfect preset
• don’t rely on standard fine-art ICC profiles
• start with a lower-ink paper setting such as plain/office paper
• use the widest platen gap if paper thickness is uncertain

A coated paper setting like velvet fine art paper is not the safest assumption for true uncoated watercolor stock.