Contrary to what you might think make sure to use a larger depth of field. So shoot at 5.6 or 4.5 and not at 2.8. Most lenses are not tack sharp at their largest aperture.

The cool factor with these types of shots comes form a razor sharp image so use a fast shutter speed as well to minimize motion (ever tried to hold your eye open without using your hands?).

If possible, use a cable or electronic shutter release mechanism to minimize vibrations. Also, if you have the ability to lock your mirror in position then do so.

You will want to manually focus the shot as well. Autofocus can move at the last minute and may or may not be sharp.

And resign yourself to the idea that you will be taking plenty of shots in an effort to get "the one"

Once you have the image you think you can work with bring it into LR. I love 4.2 so you may want to upgrade as I think it really is worth it. The controls changes from 3 to 4 and they give you a bit more finesse. Process the image paying special attention to the sharp settings (duh). That is pretty much it. You may have to tweak it a bit.

If you get a good capture and you want to give me a try with the raw file just send it over.