Yes—multi-camera control is possible, but it usually requires specialized software or trigger hardware rather than the standard utility that comes with one camera.

For USB control, some applications are designed to manage multiple cameras at once, including tools such as Breeze Systems multi-camera software, digicamControl, Smart Shooter, and similar studio/capture programs. Support varies by camera model and brand, so mixed-brand setups may work only with software that explicitly supports them.

If your main goal is firing all cameras at the same instant, hardware triggers are often the simplest option. Radio triggers and dedicated trigger boxes can synchronize several cameras and can also be expanded for larger arrays.

Changing aperture, shutter speed, and ISO across all cameras is possible only when the cameras and the chosen software support remote control of those settings. In practice, this is model-dependent and often more limited than simple synchronized triggering.

So the short answer is: yes, but not with every camera utility, and feature support depends on the specific cameras and control system.