For most uses, the standard color profile for your camera ("Adobe Standard") should be sufficient. However, you may prefer the look of one of the other profiles for specific images. According the the SpyderCheckr (Windows, Macintosh) help files:

It is recommended that the "Adobe Standard" option be selected in the camera profile popdown list in Lightroom and ACR. This is the default choice, and the only option available in most cases, unless canned or custom profiles have been imported by the user. It is possible to use any profile as the basis for SpyderCheckr calibration, but its important to remember what profile was in place when the calibration was created, and to use that same profile when processing images through the resulting camera calibration preset. So the simplest solution is to leave the DNG profile at its default.

For "most accurate colors", you would need to create custom camera profiles by photographing a color calibration chart and processing it with appropriate software to create an ICC or DCP file. A different profile for each camera and lighting setup would be needed.

How often to reshoot the chart depends on your needs. At the beginning of each session and whenever the lights are changed (position, amount, type, etc) would be reasonable. You don't have to create new profiles if they aren't needed, but you won't be able to if you don't have photos of the chart.

Other software that may be of interest:

• X-Rite ColorChecker Camera Calibration v2.0
• Adobe DNG Profile Editor
• DCamProf – open source, command line utility.

See also:

• Rawpedia: How to Create DCP Color Profiles