A practical offline approach is to use Hugin/PanoTools with a reusable project template, then run the tools from the command line. Since the Bublcam’s four fisheye lenses are fixed relative to each other, you can create and optimize a stitching project once, save it as a .pto template, and reuse it for batches of images.

Typical workflow:

1. Split each multiplexed Bublcam file into 4 separate fisheye images first (for example with ImageMagick).
2. Build a Hugin project using those 4 views, set the output projection to equirectangular, and optimize alignment.
3. Save that project as a template.
4. For each new set, feed the new images into the template and render from the command line using tools like nona, then blend with enblend.

If the camera geometry truly never changes, you should not need to manually place control points for every image. Control points are mainly needed when creating and refining the template. After that, batch reuse is the main advantage.

For HDR, process the bracketed exposures consistently within that same workflow before or during panorama assembly, depending on how you build the pipeline.