The answer to the title question is "well, no." Any post-production that can be done to help a mediocre zoom can also be applied to a prime lens. DxO Optics is raw conversion software that's designed to do exactly that, and while it has more proportionate effect on weaker lenses, even the best get a bit better.

"What I would want in answer: A proper experimented exposure setting which helps me to get an image (in a well lit environment) on which I can increase the sharpness in post production with minimal noise. Resulting in a prime quality image (atleast near.. I do understand its practically impossible but we can at least try it.)"

The key to this is to not stress the lens. Stop the aperture down one or two stops from wide open, and don't depend on the ends of its zoom range. Don't shoot directly into the light if you can avoid it, and don't use a cheap UV filter. Work at the lowest iso setting that will still give you a sharp subject – motion blur is worse than noise – use raw capture to preserve as much information as possible until you can make decisions on a bigger monitor, and consider downloading the free trial of DxO Optics to see if its specialized processing brings you closer to your goal.