No. For Nikon optical CLS/AWL, the on-camera unit must specifically support Nikon commander functionality. A random hot-shoe flash—such as a Fujifilm mini flash—cannot act as a CLS/AWL “smart” commander just because it fits the shoe.

Your compact optical options are essentially a Nikon-compatible commander such as the SU-800, or Nikon/third-party speedlights that explicitly include CLS/AWL commander capability. Many flashes can only fire in a simple optical slave mode (often called SU-4 mode), which is manual-only: it can trigger a remote flash, but you won’t get TTL, remote power control, or HSS/FP through that basic optical trigger method.

Also, optical CLS/AWL is an older system and can be harder to build around on mirrorless bodies. If you’re buying into off-camera flash now, a radio system is often the more practical path than investing heavily in optical CLS/AWL.